143 research outputs found

    Plan de comercialización para mejorar las ventas de los productos financieros en la agencia Balta de CMAC Piura, Lambayeque

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    La siguiente investigación tuvo como objetivo general realizar un plan de comercialización para mejorar las ventas de los productos financieros de Cmac piura agencia balta. La indagación fue de tipo mixta y un diseño no experimental. La población se conformó por 60 clientes. Se determinó como técnica la encuesta. Se propuso dos instrumentos de recolección de datos: el cuestionario de captación de clientes. El proceso estadístico se ejecutó mediante el programa SPSS versión 25. El cuestiona rio de fascinación de clientes sostuvo una validez y confiabilidad de 0,827 de Alfa de Cronbach. Se consideró las consecuencias: que existe un nivel de medio en la comercialización de los productos financieros, esto sucede porque no se están aplicando las estrategias adecuadas para una buena comercialización e incrementar las ventas, por lo que se propone un plan de comercialización para incrementar las ventas.TesisGestión empresarial y emprendimient

    Aerial cable-cars in Medellin: Social inclusion and reduced emissions

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    Building upon previous work of the International Resource Panel on Decoupling Natural Resource Use and Environmental Impacts from Economic Growth, this report examines the potential for decoupling at the city level. As the majority of the world’s population now lives in cities, and cities are where most resource consumption takes place, both the pressures and potential to find ways to reconcile economic growth, wellbeing and the sustainable use of natural resources will be greatest in cities. Analysing the role of cities as spatial nodes where the major resource flows connect as goods, services and waste, the report’s focus is how infrastructure directs material flows and, therefore, resource use, productivity and efficiency in an urban context. It makes the case for examining cities from a material flow perspective, while also placing the city within the broader system of flows that make it possible for it to function. The report also highlights the way that the design, construction and operation of energy, waste, water, sanitation and transport infrastructures create a socio-technical environment that shapes the “way of life” of citizens and how they procure, use and dispose of the resources they require. Its approach is innovative in that it frames infrastructure networks as socio-technical systems, examining pressures for change within cities that go beyond technical considerations. The importance of intermediaries as the dominant agents for change is emphasized, as well as the fact that social processes and dynamics need to be understood and integrated into any assessment of urban infrastructure interventions and the reconfiguration of resource flows. A set of 30 case studies provide examples of innovative approaches to sustainable infrastructure change across a broad range of urban contexts that could inspire leaders of other cities to embrace similar creative solutions. Of course, innovations in and of themselves do not suffice if they are not integrated into larger strategic visions for the city, and as each city is unique, interventions need to be tailored to the set of challenges and opportunities present in each case

    Ctenid spiders.

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    86 p. : ill. ; 26 cm.Includes bibliographical references (p. 33-39).A cladistic analysis based on parsimony is undertaken to test hypotheses concerning the monophyly of the ctenid spiders and the relationships among their various clades. The data matrix comprised a total of 98 species representing 16 families scored for 146 characters, with all but six taken from various morphological systems; the remaining are behavioral attributes. Ctenidae is shown to be polyphyletic as currently delimited, but the most severely questioned taxa (i.e., Acanthoctenus, Cupiennius, and Ancylometes) are indeed members of this family. The so-called ctenid eye pattern is shown to be a synapomorphy uniting a more restricted set of taxa. This clade is recognized as Ctenidae sensu stricto and it comprises at least five major lineages: Acantheinae, Acanthocteninae, Calocteninae, Cteninae, and Viridasiinae. The latter taxa are hypothesized to be the sister group of all other ctenids. In turn, a clade formed by Miturgidae s.s. and Zoridae s.s. is proposed as the sister group of Ctenidae. The cladistic analysis also refutes the monophyly of Ctenus, Anahita, Enoploctenus, Celaetycheus, and Leptoctenus. The following taxonomic changes are proposed: Anahita isaloensis Ono, 1993 is transferred to Vulsor Simon, 1888; Diallomus Simon, 1897, currently placed in Zoridae, is transferred to Ctenidae; Tunabo Chamberlin, 1916 is synonymized with Neoctenus Simon, 1897; Neoctenus is removed from Zoridae and transferred to Trechaleidae; Xenoctenus Mello-Leitão, 1938 is removed from the synonymy of Tunabo and considered incertae sedis, within Ctenoidea

    Neurobehavioral changes in people with post-stroke aphasia

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    At present, research on neurobehavioral disorders in people with post-stroke aphasia is scarce, especially in Spanish. The objective of this study is to design a new scale on neurobehavioral change, the Scale of Neurobehavioral Affectation in Aphasia (EANA, in Spanish) and to evaluate 14 people affected by chronic post-stroke aphasia (mean age: 51/ DT: 7.2) together with their main informants. At the same time, psychiatric (Neuropsychiatric Inventory, Hospital Anxiety and Depression Scale, Stroke Aphasic Depression Questionnaire), cognitive (Mini Mental State examination, Informer Test) and functional instruments (Stroke and Aphaisa Quality of Life Scale and Barthel Index) have been used to provide a multidimensional description of the affected persons. The results show statistically significant neurobehavioral changes in multiple domains. According to the EANA, those affected with post-stroke aphasia communicate with less frequently, show more introversion, shyness, dependence and apathy, behave in a more infantile manner ("makes me grimaces"), in addition to showing heightened anxiety and impulsivity. Finally, the informants report more aggressive acts, both verbal (insults) and physical (throwing objects, hitting both objects as persons), that did not occur before the stroke. According to the psychiatric instruments, many of the affected cope with anxiety, agitation and apathy, as well as mild depression. At a cognitive level, affected individuals show mild to moderate deficits, especially in working memory and temporal orientation. Functionally most individuals maintain a medium-high level of functional independence in daily activities. These findings support the inclusion of recommendations for the routine assessment and management of neurobehavioral changes to help optimize long-term recovery in people with stroke and aphasia.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Liderazgo directivo y desempeño laboral docente en la Institución Educativa Sagrado Corazón de Jesús, Chota en el año 2022

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    La presente investigación tuvo como objetivo general la relación que se presenta entre el liderazgo directivo y el desempeño laboral docente en la Institución Educativa Sagrado Corazón de Jesús, Chota en el año 2022; corresponde a una investigación cuantitativa de tipo básico de diseño no experimental correlacional, para lo cual se tomó una población de 32 docentes de la Institución Educativa Sagrado Corazón de Jesús de Chota, de donde se extrajo una muestra intencionada de 32 docentes, a quienes se aplicaron dos encuestas una sobre liderazgo directivo y la otra sobre desempeño laboral docente, por ser una muestra paramétrica, para la correlación de variables se calculó el coeficiente de correlación de Pearson, el mismo que arrojó un valor de 0,870 y un sig bilateral de 0,000, con lo cual se demuestra que se presenta entre las variables liderazgo directivo y desempeño laboral docente una correlación altamente significativa

    Propuesta de instalación de una planta de producción de alimento peletizado de alta densidad nutricional

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    El presente trabajo de investigación tuvo como objetivo determinar la viabilidad de la propuesta de instalación de una planta productora de alimento peletizado de alta densidad nutricional para el ganado en ordeño. De esta manera, se realizó un estudio de mercado para indicar la viabilidad comercial del producto, específicamente en los departamentos de La Libertad, Cajamarca y Lambayeque. Por ende, se estableció aprovechar el 5% de la demanda insatisfecha para los próximos 5 años. Posteriormente, se determinó la localización, teniendo como resultado para la ubicación, el departamento de La Libertad, de acuerdo a los factores determinados en relación a la macro y micro localización. Luego, se realizó el diseño técnico y tecnológico, en el cual se consideró los requerimientos de materiales e insumos, disponibilidad de materiales, así como la tecnología respecto a la maquinaria y equipos necesarios para el proceso productivo, asimismo se utilizó el método Guerchet y SLP para calcular el requerimiento del área y la distribución de la planta productora, la cual tuvo una capacidad real para el año 5 de 773 394 sacos/año. Finalmente, se ejecutó el estudio económico y financiero, para determinar la viabilidad del proyecto. Como resultado se obtuvo un Valor Neto Actual de S/ 6 003 208 y una Tasa Interna de Retorno de 45%, con un periodo de retorno de la inversión de 2 años y 6 meses, y una inversión de S/ 4 948 503,87. En consecuencia, se demuestra la viabilidad comercial, técnica y tecnológica, y económica-financiera del presente proyecto

    Aphasia with anatomical isolation of the language area: A reanalysis on the light of modern neuroimaging techniques

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    Introduction : Goldstein (1948) and Geschwind (1968), based in data derived from anatomical post-mortem studies, postulated that the disconnection of the perisylvian language areas (PSLA) from other cortical areas was responsible for impairments in spontaneous speech and language comprehension with preservation of verbal repetition and echolalia (isolation of speech area). Nevertheless, other mechanisms (right hemisphere or bilateral hypotheses) underlying echolalic repetition have been proposed. Herein, we examined the structure and function of the PSLAs in two cases of aphasia with echolalic repetition and isolation of the left PSLA. Methods : Two patients with chronic post-stroke aphasia associated to isolation of the left PSLA were studied. Both patients underwent cognitive-language assessment and multimodal imaging. In patient 1 (p1), structural MRI, diffusion tensor imaging (DTI), functional MRI (fMRI) during repetition of words and non-words, resting state fMRI (rsfMRI) were acquired, whereas only structural MRI was performed in patient 2 (p2). The Tractotron software was used to examine the severity of disconnection in each language-related white matter tract in both patients. We quantified the severity of the disconnection by measuring the proportion of each tract that was affected. 18FDG-PET was also acquired in both patients. Results : P1 had a mixed transcortical aphasia and p2 had a transcortical sensory/anomic aphasia. In both, the MRI showed separate left anterior and posterior lesions with relative preservation of the PSLA. In both, 18FDG-PET revealed significant decrements of metabolic activity in areas of the left PSLA, although some parts showed normal metabolic activity. In p1 the left arcuate fasciculus (AF) and the inferior fronto-occipital fasciculi (IFOF) could not be reconstructed. fMRI showed perilesional activity in the left hemisphere and increased activity in the right during word repetition. rsfMRI showed compensatory activity in both hemispheres (right greater than left). Analysis with the Tractotron software revealed disconnection of both the AF and the IFOF in the left hemisphere of both patients. Discussion : Although some parts of the left PSLA had preserved metabolic activity in both patients, our neuroimaging data revealed that preserved repetition ability did not rely exclusively on the residual activity of the left PSLA. In support, the connectivity between different components of the left PSLA was severely affected. This coupled with the increased metabolic activity of the right PSLA supports the bilateral hypothesis of residual repetition in transcortical aphasias. References : Goldstein, K. (1948). Language and Language Disturbances. Geschwind, et al. (1968). Neuropsychologia 6, 327–340.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

    Beneficial effects of pharmacological treatment in post-stroke dynamic aphasia: a behavioural and neuroimaging study

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    Introduction : Dynamic Aphasia (DA) is a rare form of language disorder characterized by reduced spontaneous speech with preservation of other language functions. Two types of DA have been described: language-specific type (type I DA) and domain-general type (type II DA). In type I DA, deficits are selective for word and sentence generation, whereas in type II DA impairments affect discourse generation, narrative, fluency, and non-verbal generation tasks. There is little information on the treatment of DA. Although treatment with a cognitive enhancing drug (bromocriptine) improved outcome in previous studies, pharmacological interventions combining two drugs acting on other neurotransmitter systems in DA have not been reported so far. Methods : We report an open-label pharmacological single case study (n = 1) in a male patient with a chronic type I/II DA secondary to an ischemic infarction in the left fronto-opercular and insular regions. After baseline evaluation, the patient received donepezil 5 mg/day (2 months), donepezil 10 mg/day (2 months), donepezil 10 mg/day plus memantine 20 mg/day (4½ months) followed by a washout period (1½ months). No speech-language therapy was used. A comprehensive cognitive and language evaluation was carried out at baseline and at different endpoints. 18FDG-PET was performed at the four timepoints. Results : Donepezil (5 mg/day) significantly improved type I DA features (normalization of verbs generation, p = 0.01), whereas donepezil (10 mg/day) improved some type II features (normalizing spontaneous speech, verbal fluency and improving generation of novel thoughts, p = 0.004), along with improvement of executive-attentional functioning. Combined therapy further enhanced cognitive function, but did not additionally improved DA. 18 FDG-PET revealed significant reductions of perilesional hypometabolic activity mainly after donepezil (10 mg/day) and washout. Discussion : Treatment with donepezil improved language deficits in a patient with chronic post-stroke type I/II DA. Combined therapy (donepezil plus memantine) further enhanced executive-attentional functioning. Beneficial changes were associated with improvements in perilesional metabolic activity. References : Luria AR et al.Acta Neurologica et Psychiatrica (1967). Robinson G et al. Brain (1998). Keywords : Language; patients; single case study; adults; cerebrovascular; behavioural, functional imaging.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    “Need to know” and the right temporal lobe: Impaired access to semantic knowledge in acquired obsessive-compulsive disorder?

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    Introduction : Idiopathic obsessive-compulsive disorder (I-OCD) has been linked to abnormalities in corticostriatal circuits. Few studies have examined if the same structures are also responsible of acquired OCD (A-OCD) or if damage to anatomically-connected brain regions (e.g., temporal lobes) are also implicated in its pathogenesis. Additionally, there are some discrete obsessive-compulsive (OC) symptoms that by virtue of their presumed low occurrence and difficultly of categorization have received less attention. Amongst these, one intriguing and potentially severe type of obsessive thinking is the so-called “need to know” (NtK), a strong drive to know and obtain given information. In some patients this specific symptom, presumably resulting from impaired access to conceptual knowledge for specific verbal information (proper names, names of places), may be the principal or major feature of OCD symptomatology. We here report the cases of two male patients who developed “NtK” as the only OC symptomatology in association with malignant neoplasms involving the right temporal lobe and connected corticostriatal circuits. Methods : We used Tractotron and Disconnectome map softwares in order to identify the regions of white matter damage overlap across both patients and the proportion of damage (lesion load) of each tract of interest for each patient. We quantified the severity of the disconnection by measuring the proportion of each tract of interest to be affected by each patient´s lesion by using Tractotron software. Additionally, Positron Emission Tomography was used in order to study metabolic abnormalities. The tracts of interest were: the uncinate fasciculus, the anterior commissure, the anterior thalamic radiations, the inferior fronto-occipital fasciculus and the inferior longitudinal fasciculus. Results : There was a high overlap across brain lesions in patients 1 and 2. There was also a high overlap between areas that were affected (disconnected) due to the lesion. As expected, all the a priori selected pathways in the right hemisphere were affected since they cross the anterior part of the temporal lobe. Disconnection maps and metabolic changes in our patients suggest that the expression of OC symptoms underpinned by a semantic deficit due to right temporal damage is secondary to involvement of the uncinate fasciculus linking the temporal pole with the orbitofrontal cortex. Discussion : Data from the present study concur with previous research on A-OCD and current findings in I-OCD which suggest that the temporal lobes participate in the phenomenological expression of OCD. Also, patients with lesions in the anterior temporal lobe are prone to show a specific “Need to Know” symptoms phenomenologically similar to patients with semantic dementia in later stages. The expression of OC symptoms underpinned by a semantic deficit because of anterior right temporal lobe lesion, are due to a disconnection of the uncinate fasciculus and the orbitofrontal cortex. Further research about the neurological underpinnings of specific OCD subtypes, its evaluation and treatment, are essential. References : Berthier ML et al. Neurology. (1996) 47: 353–61. Huey E et al. J Neuropsych Clin Neurosci (2008). 20(4):390-408 Keywords : Emotions & Social Cognition; patients; single case study; adults; psychiatric; lesion mapping, behavioural.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
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